研究方向

研究领域：环境健康 (Environmental Health)，环境与分子毒理学 (Environmental and Molecular Toxicology)，环境生物技术 (Environmental Biotechnology)

主要研究方向：

• 高通量表型组学 High-Throughput Phenotyping
  

• 发育毒性效应与机制 Developmental Toxicity in Early Life Stages
  

• 环境生物学大数据 Big Data in Environmental Biology

• 环境生物技术 Environmental Biotechnology

鼓励Discovery & Creation，鼓励自由探索，鼓励多学科交叉，欢迎环境、生物、化学、计算机等背景同学加入。: )

目前，团队招聘多名科研助理、博士后，具体信息见：https://postd.sjtu.edu.cn/info/1004/1928.htm

个人简历

1. 2018.09-至今，bwin必赢 长聘教轨副教授/长聘副教授
2. 2016.10-2018.08，美国哈佛大学医学院 (布莱根妇女医院) 心血管医学系 博士后
3. 2014.03-2016.07，瑞士西北应用科技大学 (生态环境研究所) 环境科学 博士后
4. 2007.09-2013.07，北京大学 环境科学 理学博士
5. 2003.09-2007.07，西北农林科技大学 生物技术 理学学士
   

1. 2018.09- Associate Professor, School of Environmental Science and Engineering, Shanghai JiaoTong University
2. 2016.10-2018.08, Postdoctoral Research Fellow, Harvard Medical School & BWH, Boston
3. 2014.03-2016.07, Postdoctoral Research Fellow, Institute of Ecopreneurship, FHNW, Switzerland
4. 2007.09-2013.07, Ph.D. in Environmental Science, Peking University
5. 2003.09-2007.07, B.Sc. in Biology, Northwest A&F University
   

研究成果

致力于环境新污染物生态毒理学效应及毒性作用机制研究。综合运用分子生物学、生物信息学和分析化学技术，围绕环境新污染物的高通量检测平台开发、毒性效应评估和毒理作用机制开展系统深入研究工作。相关研究成果在Environ. Sci. Technol.、Environ. Int.、Proc. Natl. Acad. Sci. U.S.A.等环境领域及重要国际综合类SCI期刊上发表论文50余篇，其中第一作者/通讯作者论文30余篇。先后主持上海市浦江人才计划项目、国家自然科学基金面上项目、国家自然科学基金优秀青年基金项目等科研项目。曾获瑞士FHNW生态环境研究所年度杰出论文奖，任J. Hazard Mater.专刊编委，ACS ES&T Water杂志编委会。

代表性论著

1. Wang, C.; Li, M.; Gui, W.; Shi, H.; Wang, P.; Chen, J.; Fent, K.; Zhang, K.; Dai, J.; Li, X.; Zhao, Y. B.* Prednisolone Accelerates Embryonic Development of Zebrafish via Glucocorticoid Receptor Signaling at Low Concentrations. Environ. Sci. Technol. 2023 , 57 (42), 15794-15805.
   
2. Shi, H.; Li, M.; Meng, H.; Zheng, X.; Zhang, K.; Fent, K.; Dai, J.; Zhao, Y. B.* Reduced Transcriptome Analysis of Zebrafish Embryos Prioritizes Environmental Compounds with Adverse Cardiovascular Activities. Environ. Sci. Technol. 2023, 57 (12), 4959-4970.
   
3. Zhang, K.; Liang, J.; Brun, N. R.; Zhao, Y. B.*; Werdich, A. A. Rapid Zebrafish Behavioral Profiling Assay Accelerates the Identification of Environmental Neurodevelopmental Toxicants. Environ. Sci. Technol. 2021, 55 (3):1919-1929.
4. Zhao, Y. B.; Liang, J.; Meng, H.; Yin, Y.; Zhen, H.; Zheng, X.; Shi, H.; Wu, X.; Zu, Y.; Wang, B.; Fan, L.; Zhang, K.* Rare Earth Elements Lanthanum and Praseodymium Adversely Affect Neural and Cardiovascular Development in Zebrafish. Environ. Sci. Technol. 2021, 55 (2):1155-1166.

5. Zheng, X. H.; Zhang, K.; Zhao, Y. B.*; Fent, K.* Environmental Chemicals Affect Circadian Rhythms: an Underexplored Effect Influencing Health and Fitness in Animals and Humans. Environ. Int. 2021, 106159.

6. Zhao, Y. B.; Zhang, K.*; Xu, X.T.; Shen, H. Z.; Zhu, X.; Zhang, Y. X.; Hu, Y. T.; Shen, G. F. Substantial Changes in Nitrogen Dioxide and Ozone after Excluding Meteorological Impacts during the COVID-19 Outbreak in Mainland China. Environ. Sci. Technol. Lett. 2020, 7, 402-408. (Highlight, High Cited)

7. Zhang, K.; Zhao, Y. B.* Reduced Zebrafish Transcriptome Atlas toward Understanding Environmental Neurotoxicants. Environ. Sci. Technol. 2018, 52 (12), 7120-7130.
8. Zhao, Y. B.; Zhang, K.; Fent, K. Corticosteroid Fludrocortisone Acetate Targets Multiple End Points in Zebrafish at Low Concentrations. Environ. Sci. Technol. 2016, 50 (18), 10245-10254.
9. Zhao, Y. B.; Castiglioni, S.; Fent, K. Environmental Progestins Progesterone and Drospirenone Alter the Circadian Rhythm Network in Zebrafish. Environ. Sci. Technol. 2015, 49 (16), 10155-10164.

10. Zhao, Y. B.; Castiglioni, S.; Fent, K. Synthetic Progestins Medroxyprogesterone Acetate and Dydrogesterone and Their Binary Mixtures Adversely Affect Reproduction and Lead to Histological and Transcriptional Alterations in Zebrafish (Danio rerio). Environ. Sci. Technol. 2015, 49 (7), 4636-4645.